Omeprazole is a specific inhibitor of the proton-pump of the parietal cell. Taken once a day, it affects reversible inhibition of gastric acid secretion. Omeprazole is a racemic mixture of 2 active enantiomers, reduces gastric acid secretion via a targeted mechanism of action.
Omeprazole is a weak base which is concentrated and converted into the active form in the strongly acidic area of the intracellular canaliculi of the parietal cell, where it inhibits the enzyme H+/K+-ATPase, the proton pump.
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